The use of liver grafts infested with Clonorchis sinensis for orthotopic liver transplantation.

The use of liver grafts infested with Clonorchis sinensis for orthotopic liver transplantation.

In the Orient, millions are known to have Clonorchis sinensis (biliary trematodiasis) infestation. When these infested livers become available as donor organs, there are potentially serious implications that the transplant team would need to consider. We report the use of two such infested livers, one from a cadaveric donor and the other from a live related donor, for orthotopic liver transplan...

LIVER TRANSPLANTATION Personal Experience With Orthotopic Liver

I N this communication we will discuss three questions about orthotopic liver transplantation (liver replacement). First, what are the indications for hepatic transplantation? Second, what have been the results? Third, what is the outlook for improving these figures? Orthotopic liver transplantation is often difficult, mainly because of the liver pathology that essentially always creates severe...

Orthotopic liver transplantation for alcoholic liver disease.

Alcohol abuse is the most common cause of end-stage liver disease in the United States, but many transplant centers are unwilling to accept alcoholic patients because of their supposed potential for recidivism, poor compliance with the required immunosuppression regimen and resulting failure of the allograft. There is also concern that alcohol-induced injury in other organs will preclude a good...

Human orthotopic liver transplantation: surgical aspects in 393 consecutive grafts.

Developmental Transcriptomic Features of the Carcinogenic Liver Fluke, Clonorchis sinensis

Clonorchis sinensis is the causative agent of the life-threatening disease endemic to China, Korea, and Vietnam. It is estimated that about 15 million people are infected with this fluke. C. sinensis provokes inflammation, epithelial hyperplasia, and periductal fibrosis in bile ducts, and may cause cholangiocarcinoma in chronically infected individuals. Accumulation of a large amount of biologi...